Dermal and extra-dermal manifestations of gadolinium-triggered nephrogenic fibrosing dermopathy

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Dermal and extra-dermal manifestations of gadolinium-triggered nephrogenic fibrosing dermopathy.

We thank Dr Grzegorzewka for sharing her results on serum OPG and RANKL levels in dialysis population. With respect to her comments regarding our study, our objective was not to focus on markers, but to use them as a tool for interpretating phosphate elimination. However, we found (results not shown in the manuscript) that OPG serum levels were lower in patients with adynamic disease than in th...

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Gadolinium deposition in nephrogenic fibrosing dermopathy.

There is growing recognition of the association between the use of gadolinium-containing radiocontrast agents for magnetic resonance imaging and the serious dermal and systemic disease nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis (NFD/NSF). The pathogenesis of this entity remains unclear; however, our recent observations suggest a likely mechanism for the initial dermal manife...

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INTRODUCTION Nephrogenic fibrosing dermopathy is a recently recognised fibrosing disorder originally identified as a scleromyxoedema-like cutaneous disease in patients with renal disease. CLINICAL PICTURE A 45-year-old lady with systemic lupus erythematosus presented with well-defined erythematous, non-tender, indurated plaques on both legs 4 months after haemodialysis for rapidly progressive...

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Nephrogenic fibrosing dermopathy: report of two cases.

Nephrogenic fibrosing dermopathy is a recently described fibrosing disorder that emerges in different settings of renal insufficiency. The degree and cause of the underlying renal impairment seem not to be related to the severity of the nephrogenic fibrosing dermopathy. Lesions are typically symmetrical and usually develop on the limbs and trunk. These are characterized by skin-coloured to eryt...

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A 47-year-old woman presented with a 2-month history of progressive tightening of the skin on her legs. The tightening of her skin had begun 2 weeks after she was hospitalized for acute renal failure precipitated by therapy with nonsteroidal anti-inflammatory drugs. She had no history of renal disease or medical conditions that would predispose her to the organ failure. During her hospitalizati...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2006

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/gfl592